論文
350.
Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity.
Tadokoro T, Ikeda M, Ide T, Deguchi H, Ikeda S, Okabe K, Ishikita A, Matsushima S, Koumura T, Yamada KI, Imai H, Tsutsui H.
JCI Insight. 2020 May 7;5(9)
349.
Aberrant activation of bone marrow Ly6C high monocytes in diabetic mice contributes to impaired glucose tolerance.
Ikeda Y, Sonoda N, Bachuluun B, Kimura S, Ogawa Y, Inoguchi T.
PLoS One. 2020 Feb 25;15(2)
348.
RagA, an mTORC1 activator, interacts with a hedgehog signaling protein, WDR35/IFT121.
Sekiguchi T, Furuno N, Ishii T, Hirose E, Sekiguchi F, Wang Y, Kobayashi H.
Genes Cells. 2019 Feb;24(2):151-161.
347.
Src Mediates Epigallocatechin-3-O-Gallate-Elicited Acid Sphingomyelinase Activation.
Kumazoe M, Kadomatsu M, Bae J, Otsuka Y, Fujimura Y, Tachibana H.
Molecules. 2020 Nov 23;25(22):5481.
346.
Reduced Post-ischemic Brain Injury in Transient Receptor Potential Vanilloid 4 Knockout Mice.
Tanaka K, Matsumoto S, Yamada T, Yamasaki R, Suzuki M, Kido MA, Kira JI.
Front Neurosci. 2020 May 12;14:453.
345.
SPOCK1 is a novel inducer of epithelial to mesenchymal transition in drug-induced gingival overgrowth.
Alshargabi R, Sano T, Yamashita A, Takano A, Sanada T, Iwashita M, Shinjo T, Fukuda T, Sanui T, Kishida S, Nishimura F.
Sci Rep. 2020 Jun 17;10(1):9785.
344.
GRK5 Inhibition Attenuates Cartilage Degradation via Decreased NF-κB Signaling.
Sueishi T, Akasaki Y, Goto N, Kurakazu I, Toya M, Kuwahara M, Uchida T, Hayashida M, Tsushima H, Bekki H, Lotz MK, Nakashima Y.
Arthritis Rheumatol. 2020 Apr;72(4):620-631.
343.
Fluorescence detection of metabolic activity of the fatty acid beta oxidation pathway in living cells.
Uchinomiya S, Matsunaga N, Kamoda K, Kawagoe R, Tsuruta A, Ohdo S, Ojida A.
Chem Commun (Camb). 2020 Mar 10;56(20):3023-3026.
342.
The balance of forces generated by kinesins controls spindle polarity and chromosomal heterogeneity in tetraploid cells.
Shu S, Iimori M, Wakasa T, Ando K, Saeki H, Oda Y, Oki E, Maehara Y.
J Cell Sci. 2019 Dec 13;132(24):jcs231530.
341.
Cytotoxicity of trifluridine correlates with the thymidine kinase 1 expression level.
Kataoka Y, Iimori M, Niimi S, Tsukihara H, Wakasa T, Saeki H, Oki E, Maehara Y, Kitao H.
Sci Rep. 2019 May 28;9(1):7964.
340.
Intramolecular Interaction in LGN, an Adaptor Protein That Regulates Mitotic Spindle Orientation
Hiroki Takayanagi 1 , Junya Hayase 1 , Sachiko Kamakura 1 , Kei Miyano 1 , Kanako Chishiki 1 , Satoru Yuzawa 1 , Hideki Sumimoto 2
Front Immunol. 2020 Mar 11;11:432.
339.
Inhibition of PI3Kδ Enhances Poly I:C-Induced Antiviral Responses and Inhibits Replication of Human Metapneumovirus in Murine Lungs and Human Bronchial Epithelial Cells.
Fujita A, Kan-O K, Tonai K, Yamamoto N, Ogawa T, Fukuyama S, Nakanishi Y, Matsumoto K.
J Biol Chem. 2019 Dec 20;294(51):19655-19666.
338.
The TRPV4-AKT axis promotes oral squamous cell carcinoma cell proliferation via CaMKII activation.
Fujita A, Kan-O K, Tonai K, Yamamoto N, Ogawa T, Fukuyama S, Nakanishi Y, Matsumoto K.
Lab Invest. 2020 Feb;100(2):311-323.
337.
Insulin deficiency promotes formation of toxic amyloid-β42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model.
Imamura T, Yanagihara YT, Ohyagi Y, Nakamura N, Iinuma KM, Yamasaki R, Asai H, Maeda M, Murakami K, Irie K, Kira JI.
Neurobiol Dis. 2020 Apr;137:104739.
336.
GRWD1 directly interacts with p53 and negatively regulates p53 transcriptional activity.
Fujiyama H, Tsuji T, Hironaka K, Yoshida K, Sugimoto N, Fujita M.
J Biochem. 2020 Jan 1;167(1):15-24.
335.
Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10.
Yokoyama T, Yukuhiro M, Iwasaki Y, Tanaka C, Sankoda K, Fujiwara R, Shibuta A, Higashi T, Motoyama K, Arima H, Yoshida K, Sugimoto N, Morimoto H, Kosako H, Ohshima T, Fujita M.
Sci Rep. 2019 Nov 14;9(1):16825.
334.
UDP-Glucuronosyltransferase (UGT)-mediated attenuations of cytochrome P450 3A4 activity: UGT isoform-dependent mechanism of suppression.
Miyauchi Y, Tanaka Y, Nagata K, Yamazoe Y, Mackenzie PI, Yamada H, Ishii Y.
Br J Pharmacol. 2020 Mar;177(5):1077-1089.
333.
Advantage of a Co-expression System for Estimating Physiological Effects of Functional Interaction Between Cytochrome P450 3A4 and Uridine ... al interaction of CYP3A4 and UGT2B7 by simply mixing the microsomes.
Miyauchi Y, Yamada H, Ishii Y.
BPB Reports 2, 61-66 (2019)
332.
Investigation of the Endoplasmic Reticulum Localization of UDP-Glucuronosyltransferase 2B7 with Systematic Deletion Mutants.
Miyauchi Y, Kimura S, Kimura A, Kurohara K, Hirota Y, Fujimoto K, Mackenzie PI, Tanaka Y, Ishii Y.
Mol Pharmacol. 2019 May;95(5):551-562.
331.
Cancer cell selective probe by mimicking EGCG.
Kumazoe M, Hiroi S, Tanimoto Y, Miyakawa J, Yamanouchi M, Suemasu Y, Yoshitomi R, Murata M, Fujimura Y, Takahashi T, Tanaka H, Tachibana H.
Biochem Biophys Res Commun. 2020 Mar 12. pii: S0006-291X(20)30496-4.
330.
Identification of ZBTB24 protein domains and motifs for heterochromatin localization and transcriptional activation.
Aktar S, Sasaki H, Unoki M.
Genes Cells. 2019 Nov;24(11):746-755.
329.
Effects of cigarette smoke on barrier function and tight junction proteins in the bronchial epithelium: protective role of cathelicidin LL-37.
Tatsuta M, Kan-O K, Ishii Y, Yamamoto N, Ogawa T, Fukuyama S, Ogawa A, Fujita A, Nakanishi Y, Matsumoto K.
Respir Res. 2019 Nov 9;20(1):251.
328.
Enhanced junctional epithelial permeability in TRPV4-deficient mice.
Kitsuki T, Yoshimoto RU, Aijima R, Hatakeyama J, Cao AL, Zhang JQ, Ohsaki Y, Mori Y, Kido MA.
J Periodontal Res. 2019 Jul 25.
327.
Expanded polyglutamine impairs normal nuclear distribution of fused in sarcoma and poly (rC)-binding protein 1 in Huntington's disease.
Mori S, Honda H, Ishii T, Yoshimura M, Sasagasako N, Suzuki SO, Taniwaki T, Iwaki T.
Neuropathology. 2019 Oct;39(5):358-367.
326.
Dynactin is involved in Lewy body pathology.
Shen C, Honda H, Suzuki SO, Maeda N, Shijo M, Hamasaki H, Sasagasako N, Fujii N, Iwaki T.
Neuropathology. 2018 Dec;38(6):583-590.
325.
Mitochondrial dysfunction and altered ribostasis in hippocampal neurons with cytoplasmic inclusions of multiple system atrophy.
Maeda N, Honda H, Suzuki SO, Fujii N, Kira JI, Iwaki T.
Neuropathology. 2018 Jul 1.
324.
Hypoxia induces the dormant state in oocytes through expression of Foxo3.
Shimamoto S, Nishimura Y, Nagamatsu G, Hamada N, Kita H, Hikabe O, Hamazaki N, Hayashi K.
Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12321-12326.
323.
Impaired Junctions and Invaded Macrophages in Oral Epithelia With Oral Pain.
Yoshimoto RU, Aijima R, Ohyama Y, Yoshizumi J, Kitsuki T, Ohsaki Y, Cao AL, Danjo A, Yamashita Y, Kiyoshima T, Kido MA.
J Histochem Cytochem. 2019 Apr;67(4):245-256.
322.
Depolysulfidation of Drp1 induced by low-dose methylmercury exposure increases cardiac vulnerability to hemodynamic overload.
Nishimura A, Shimoda K, Tanaka T, Toyama T, Nishiyama K, Shinkai Y, Numaga-Tomita T, Yamazaki D, Kanda Y, Akaike T, Kumagai Y, Nishida M.
Sci Signal. 2019 Jun 25;12(587). pii: eaaw1920.
321.
Ibudilast attenuates doxorubicin-induced cytotoxicity by suppressing formation of TRPC3 channel and NADPH oxidase 2 protein complexes.
Nishiyama K, Numaga-Tomita T, Fujimoto Y, Tanaka T, Toyama C, Nishimura A, Yamashita T, Matsunaga N, Koyanagi S, Azuma YT, Ibuki Y, Uchida K, Ohdo S, Nishida M.
Br J Pharmacol. 2019 Sep;176(18):3723-3738.
320.
Mechanical stress accompanied with nuclear rotation is involved in the dormant state of mouse oocytes.
Nagamatsu G, Shimamoto S, Hamazaki N, Nishimura Y, Hayashi K.
Sci Adv. 2019 Jun 26;5(6):eaav9960.
319.
The expression of keratan sulfate reveals a unique subset of microglia in the mouse hippocampus after pilocarpine-induced status epileptics.
Ohgomori T, Jinno S.
J Comp Neurol. 2019 Jun 25.
318.
Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis.
Harada Y, Zhang J, Imari K, Yamasaki R, Ni J, Wu Z, Yamamoto K, Kira JI, Nakanishi H, Hayashi Y.
Pain. 2019 Apr 30.
317.
Stromal Interaction Molecule Deficiency in T Cells Promotes Spontaneous Follicular Helper T Cell Development and Causes Type 2 Immune Disorders.
Oh-Hora M, Lu X, Shiokawa M, Takayanagi H, Yamasaki S.
J Immunol. 2019 May 1;202(9):2616-2627.
316.
Wnt/β-catenin signaling, which is activated in odontomas, reduces Sema3A expression to regulate odontogenic epithelial cell proliferation and tooth germ development.
Fujii S, Nagata K, Matsumoto S, Kohashi KI, Kikuchi A, Oda Y, Kiyoshima T, Wada N.
Sci Rep. 2019 Mar 12;9(1):4257.
315.
Inhibiting the MCM8-9 complex selectively sensitizes cancer cells to cisplatin and olaparib.
Morii I, Iwabuchi Y, Mori S, Suekuni M, Natsume T, Yoshida K, Sugimoto N, Kanemaki MT, Fujita M.
Cancer Sci. 2019 Mar;110(3):1044-1053.
314.
GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.
Watanabe S, Fujiyama H, Takafuji T, Kayama K, Matsumoto M, Nakayama KI, Yoshida K, Sugimoto N, Fujita M.
J Cell Sci. 2018 Aug 3;131(15).
313.
Association of Missense Polymorphism in HSD3B1 With Outcomes Among Men With Prostate Cancer Treated With Androgen-Deprivation Therapy or Abiraterone.
Shiota M, Narita S, Akamatsu S, Fujimoto N, Sumiyoshi T, Fujiwara M, Uchiumi T, Habuchi T, Ogawa O, Eto M.
JAMA Netw Open. 2019 Feb 1;2(2):e190115.
312.
The transcription factor NKX2-3 mediates p21 expression and ectodysplasin-A signaling in the enamel knot for cusp formation in tooth development.
Han X, Yoshizaki K, Miyazaki K, Arai C, Funada K, Yuta T, Tian T, Chiba Y, Saito K, Iwamoto T, Yamada A, Takahashi I, Fukumoto S.
J Biol Chem. 2018 Sep 21;293(38):14572-14584.
311.
Establishment of a rapid and simple assay for measuring serum trehalase activity.
Terada S, Sakemoto M, Kawanobe Y, Kawano M, Tateishi T, Hotta T, Kang D, Kayamori Y and Hokazono E.
Int J Anal Bio-Sci, 6, 2, 19-24, Vol. 6, No2 (2018), 2018.06
310.
Folic acid-mediated mitochondrial activation for protection against oxidative stress in human dental pulp stem cells derived from deciduous teeth.
Zhang Y, Kato H, Sato H, Yamaza H, Hirofuji Y, Han X, Masuda K, Nonaka K.
Biochem Biophys Res Commun. 2019 Jan 15;508(3):850-856.
309.
Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion.
Matsuda T, Irie T, Katsurabayashi S, Hayashi Y, Nagai T, Hamazaki N, Adefuin AMD, Miura F, Ito T, Kimura H, Shirahige K, Takeda T, Iwasaki K, Imamura T, Nakashima K.
Neuron. 2018 Dec 28.
308.
Osteoblastic differentiation improved by bezafibrate-induced mitochondrial biogenesis in deciduous tooth-derived pulp stem cells from a child with Leigh syndrome.
Han X, Nonaka K, Kato H, Yamaza H, Sato H, Kifune T, Hirofuji Y, Masuda K.
Biochem Biophys Rep. 2018 Nov 28;17:32-37.
307.
Effects of Derinat on ischemia-reperfusion-induced pressure ulcer mouse model.
Liu J, Rybakina EG, Korneva EA, Noda M.
J Pharmacol Sci. 2018 Oct;138(2):123-130.
306.
Neuropathic pain inhibitor, RAP-103, is a potent inhibitor of microglial CCL1/CCR8.
Noda M, Tomonaga D, Kitazono K, Yoshioka Y, Liu J, Rousseau JP, Kinkead R, Ruff MR, Pert CB.
Neurochem Int. 2018 Oct;119:184-189.
305.
Altered development of dopaminergic neurons differentiated from stem cells from human exfoliated deciduous teeth of a patient with Down syndrome.
Pham TTM, Kato H, Yamaza H, Masuda K, Hirofuji Y, Sato H, Nguyen HTN, Han X, Zhang Y, Taguchi T, Nonaka K.
BMC Neurol. 2018 Aug 31;18(1):132.
304.
The DnaA AAA+ Domain His136 Residue Directs DnaB Replicative Helicase to the Unwound Region of the Replication Origin, oriC.
Sakiyama Y, Nishimura M, Hayashi C, Akama Y, Ozaki S, Katayama T.
Front Microbiol. 2018 Aug 31;9:2017.
303.
Np95/Uhrf1 regulates tumor suppressor gene expression of neural stem/precursor cells, contributing to neurogenesis in the adult mouse brain.
Murao N, Matsubara S, Matsuda T, Noguchi H, Mutoh T, Mutoh M, Koseki H, Namihira M, Nakashima K.
Neurosci Res. 2018 May 31.
302.
HMGB2 expression is associated with transition from a quiescent to an activated state of adult neural stem cells.
Kimura A, Matsuda T, Sakai A, Murao N, Nakashima K.
Dev Dyn. 2018 Jan;247(1):229-238.
301.
Regulatory dynamics in the ternary DnaA complex for initiation of chromosomal replication in Escherichia coli.
Sakiyama Y, Kasho K, Noguchi Y, Kawakami H, Katayama T.
Nucleic Acids Res. 2017 Dec 1;45(21):12354-12373.
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