支援センターの機器・施設など(技術指導・受託を含む)をご利用されて、成果を発表される場合には 謝辞(Acknowledgments)部分に以下の一文を入れていただきますようお願い申し上げます。

▶ 謝辞(Acknowledgments)等の文例1
【日本語】 「九州大学大学院医学研究院附属ヒト疾患モデルセンター 教育・研究支援センターに技術的なサポートを頂きました。」 
【英語】 We appreciate the technical assistance from The Research Support Center, Research Center for Human Disease Modeling, Kyushu University Graduate School of Medical Sciences.

▶ 謝辞(Acknowledgments)等の文例2
【日本語】 九州大学大学院医学研究院附属ヒト疾患モデルセンター 教育・研究支援センター [ 担当者名 ] に技術的なサポートを頂きました。 
【英語】 We would like to thank [ 担当者名 ] for technical assistance at The Research Support Center, Research Center for Human Disease Modeling, Kyushu University Graduate School of Medical Sciences.




【 論文一覧 】    全400報  2022/08/18 現在

Extracellular vesicles derived from GMSCs stimulated with TNF-α and IFN-α promote M2 macrophage polarization via enhanced CD73 and CD5L expression.
  Watanabe Y, Fukuda T, Hayashi C, Nakao Y, Toyoda M, Kawakami K, Shinjo T, Iwashita M, Yamato H, Yotsumoto K, Taketomi T, Uchiumi T, Sanui T, Nishimura F.
  Sci Rep. 2022 Aug 3;12(1):13344.

Low-dose sodium-glucose cotransporter 2 inhibitor ameliorates ischemic brain injury in mice through pericyte protection without glucose-lowering effects.
  Takashima M, Nakamura K, Kiyohara T, Wakisaka Y, Hidaka M, Takaki H, Yamanaka K, Shibahara T, Wakisaka M, Ago T, Kitazono T.
  Commun Biol. 2022 Jul 2;5(1):653.

XAF1 overexpression exacerbates diabetes by promoting pancreatic β-cell apoptosis.
  Nishimura Y, Iwashita M, Hayashi M, Shinjo T, Watanabe Y, Zeze T, Yamashita A, Fukuda T, Sanui T, Sano T, Asano T, Nishimura F.
  Acta Diabetol. 2022 Jul 13.

ATP8B2-Mediated Asymmetric Distribution of Plasmalogens Regulates Plasmalogen Homeostasis and Plays a Role in Intracellular Signaling.
  Honsho M, Mawatari S, Fujiki Y.
  Front Mol Biosci. 2022 Jun 27;9:915457. 

Ca2+ -induced structural changes and intramolecular interactions in N-terminal region of diacylglycerol kinase alpha.
  Takahashi D, Yonezawa K, Okizaki Y, Caaveiro JMM, Ueda T, Shimada A, Sakane F, Shimizu N.
  Protein Sci. 2022 Jul;31(7):e4365.  

Myricetin improves cognitive function in SAMP8 mice and upregulates brain-derived neurotrophic factor and nerve growth factor.
  Shimada Y, Sato Y, Kumazoe M, Kitamura R, Fujimura Y, Tachibana H.
  Biochem Biophys Res Commun. 2022 May 20;616:33-40. 

Pituitary luteinizing hormone synthesis starts in aromatase (cyp19a1b)-positive cells expressing esr1 and esr2b at the onset of puberty in Takifugu rubripes (fugu).
  Yamaguchi A, Tsunematsu T, Motojima Y, Toriyama K, Horinouchi A, Ishii Y, Murata H, Yoshikawa S, Nyuji M, Shimizu A.
  Cell Tissue Res. 2022 May 13. 

Clinical impact of HSD3B1 polymorphism by metastatic volume and somatic HSD3B1 alterations in advanced prostate cancer.
  Shiota M, Fujimoto N, Sekino Y, Tsukahara S, Nagakawa S, Takamatsu D, Abe T, Kinoshita F, Ueda S, Ushijima M, Matsumoto T, Kashiwagi E, Inokuchi J, Uchiumi T, Oda Y, Eto M.
  Andrologia. 2022 Feb;54(1):e14307.  

Nectin cell adhesion molecule 4 regulates angiogenesis through Src signaling and serves as a novel therapeutic target in angiosarcoma.
  Tanaka Y, Murata M, Tanegashima K, Oda Y, Ito T.
  Sci Rep. 2022 Mar 7;12(1):4031. 

MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer's Disease.
  Mizuno Y, Abolhassani N, Mazzei G, Sakumi K, Saito T, Saido TC, Ninomiya T, Iwaki T, Yamasaki R, Kira JI, Nakabeppu Y.
  Oxid Med Cell Longev. 2021 Dec 21;2021:8635088. 

Fustin, a Flavanonol, Synergically Potentiates the Anticancer Effect of Green Tea Catechin Epigallocatechin-3-O-Gallate with Activation of the eNOS/cGMP Axis.
  Kumazoe M, Fujimura Y, Yoshitomi R, Shimada Y, Tachibana H.
  J Agric Food Chem. 2022 Mar 23;70(11):3458-3466. 

Negative feedback for DARS2-Fis complex by ATP-DnaA supports the cell cycle-coordinated regulation for chromosome replication.
  Miyoshi K, Tatsumoto Y, Ozaki S, Katayama T.
  Nucleic Acids Res. 2021 Dec 16;49(22):12820-12835. 

Phytoestrogen genistein modulates neuron-microglia signaling in a mouse model of chronic social defeat stress.
  Fujikawa R, Yamada J, Iinuma KM, Jinno S.
  Neuropharmacology. 2022 Mar 15;206:108941.

RAF1-MEK/ERK pathway-dependent ARL4C expression promotes ameloblastoma cell proliferation and osteoclast formation.
  Fujii S, Ishibashi T, Kokura M, Fujimoto T, Matsumoto S, Shidara S, Kurppa KJ, Pape J, Caton J, Morgan PR, Heikinheimo K, Kikuchi A, Jimi E, Kiyoshima T.
  J Pathol. 2022 Jan;256(1):119-133.

Compound screening identified gossypetin and isoquercitrin as novel inhibitors for amyloid fibril formations of Vλ6 proteins associated with AL amyloidosis.
  Takahashi D, Matsunaga E, Yamashita T, Caaveiro JMM, Abe Y, Ueda T.
  Biochem Biophys Res Commun. 2022 Mar 12;596:22-28.

Involvement of Gtr1p in the oxidative stress response in yeast Saccharomyces cerevisiae.
  Sekiguchi T, Ishii T, Kamada Y, Funakoshi M, Kobayashi H, Furuno N.
  Biochem Biophys Res Commun. 2022 Feb 8;598:107-112. 

Methylation-mediated silencing of protein kinase C zeta induces apoptosis avoidance through ATM/CHK2 inactivation in dedifferentiated chondrosarcoma.
  Shimada E, Matsumoto Y, Nakagawa M, Susuki Y, Endo M, Setsu N, Fujiwara T, Iida K, Nabeshima A, Yahiro K, Kimura A, Hirose T, Kanahori M, Oyama R, Oda Y, Nakashima Y.
  Br J Cancer. 2022 Jan 11.

Hypoxia-inducible factor-1 α deletion in myeloid lineage attenuates hypoxia-induced pulmonary hypertension.
  Kojima H, Tokunou T, Takahara Y, Sunagawa K, Hirooka Y, Ichiki T, Tsutsui H.
  Physiol Rep. 2019 Apr;7(7):e14025. 

Amelioration of diabetic nephropathy by SGLT2 inhibitors independent of its glucose-lowering effect: A possible role of SGLT2 in mesangial cells.
  Maki T, Maeno S, Maeda Y, Yamato M, Sonoda N, Ogawa Y, Wakisaka M, Inoguchi T.
  Sci Rep. 2019 Mar 18;9(1):4703. 

TRF2-mediated ORC recruitment underlies telomere stability upon DNA replication stress.
  Higa M, Matsuda Y, Fujii J, Sugimoto N, Yoshida K, Fujita M.
  Nucleic Acids Res. 2021 Dec 2;49(21):12234-12251. 

Redox-dependent internalization of the purinergic P2Y6 receptor limits colitis progression.
  Nishiyama K, Nishimura A, Shimoda K, Tanaka T, Kato Y, Shibata T, Tanaka H, Kurose H, Azuma YT, Ihara H, Kumagai Y, Akaike T, Eaton P, Uchida K, Nishida M.
  Sci Signal. 2022 Jan 11;15(716):eabj0644.

Ustekinumab Improves Active Crohn's Disease by Suppressing the T Helper 17 Pathway.
  Ihara Y, Torisu T, Miyawaki K, Umeno J, Kawasaki K, Hirano A, Fujioka S, Fuyuno Y, Matsuno Y, Sugio T, Sasaki K, Moriyama T, Akashi K, Kitazono T.
  Digestion. 2021;102(6):946-955. 

Integration of Single-Cell RNA- and CAGE-seq Reveals Tooth-Enriched Genes.
  Chiba Y, Yoshizaki K, Tian T, Miyazaki K, Martin D; Genomics and Computational Biology Core, Saito K, Yamada A, Fukumoto S.
  J Dent Res. 2021 Nov 20:220345211049785. 

Merkel cell polyomavirus-negative Merkel cell carcinoma is associated with JAK-STAT and MEK-ERK pathway activation.
  Iwasaki T, Hayashi K, Matsushita M, Nonaka D, Kohashi K, Kuwamoto S, Umekita Y, Oda Y.
  Cancer Sci. 2021 Nov 1. 

Association of PD-L1 and IDO1 expression with JAK-STAT pathway activation in soft-tissue leiomyosarcoma.
  Iwasaki T, Kohashi K, Toda Y, Ishihara S, Yamada Y, Oda Y.
  J Cancer Res Clin Oncol. 2021 May;147(5):1451-1463.

Short single-stranded DNAs with putative non-canonical structures comprise a new class of plasma cell-free DNA.
  Hisano O, Ito T, Miura F.
  BMC Biol. 2021 Oct 14;19(1):225.

Catalytically inactive Cas9 impairs DNA replication fork progression to induce focal genomic instability.
  Doi G, Okada S, Yasukawa T, Sugiyama Y, Bala S, Miyazaki S, Kang D, Ito T.
  Nucleic Acids Res. 2021 Jan 25;49(2):954-968. 

Early-life midazolam exposure persistently changes chromatin accessibility to impair adult hippocampal neurogenesis and cognition.
  Doi H, Matsuda T, Sakai A, Matsubara S, Hoka S, Yamaura K, Nakashima K.
  Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e2107596118.

Imaging Changes and Immune-Checkpoint Expression on T Cells in Bronchoalveolar Lavage Fluid from Patients with Pulmonary Sarcoidosis.
  Kotetsu Y, Yanagihara T, Suzuki K, Ando H, Eto D, Hata K, Arimura-Omori M, Yamamoto Y, Harada E, Hamada N.
  Biomedicines. 2021 Sep 16;9(9):1231. 

Generation of ovarian follicles from mouse pluripotent stem cells.
  Yoshino T, Suzuki T, Nagamatsu G, Yabukami H, Mika Ikegaya, Kishima M, Kita H, Imamura T, Nakashima K, Nishinakamura R, Tachibana M, Inoue M, Shima Y, Morohashi K, Hayashi K.
  Science. Volume 373(6552):eabe0237 16-Jul-21.

Incense smoke-induced oxidative stress disrupts tight junctions and bronchial epithelial barrier integrity and induces airway hyperresponsiveness in mouse lungs.
  Yamamoto N, Kan-O K, Tatsuta M, Ishii Y, Ogawa T, Shinozaki S, Fukuyama S, Nakanishi Y, Matsumoto K.
  Sci Rep. 2021 Mar 31;11(1):7222. 

Adipose-specific C-C motif chemokine ligand (CCL) 19 overexpression drives the mice to both insulin resistance and weight gain.
  Hayashi M, Iwashita M, Nishimura Y, Shinjo T, Sano T, Yamashita A, Fukuda T, Sanui T, Asano T, Nishimura F.
  BMJ Open Diabetes Res Care. 2021 May;9(1):e001871.   

Gene expression and functional abnormalities in XX/Sry Leydig cells.
  Yanai S, Baba T, Inui K, Miyabayashi K, Han S, Inoue M, Takahashi F, Kanai Y, Ohkawa Y, Choi MH, Morohashi KI.
  Sci Rep. 2021 Jan 12;11(1):719. 

Early postnatal allergic airway inflammation induces dystrophic microglia leading to excitatory postsynaptic surplus and autism-like behavior.
  Saitoh BY, Tanaka E, Yamamoto N, Kruining DV, Iinuma K, Nakamuta Y, Yamaguchi H, Yamasaki R, Matsumoto K, Kira JI.
  Brain Behav Immun. 2021 Apr 20:S0889-1591(21)00165-3.  

CADM1 and CADM2 triggers neuropathogenic measles virus-mediated membrane fusion by acting in cis.
  Shirogane Y, Takemoto R, Suzuki T, Kameda T, Nakashima K, Hashiguchi T, Yanagi Y.
  J Virol. 2021 Apr 28:JVI.00528-21. 

Gene expression profiling of α-gustducin-expressing taste cells in mouse fungiform and circumvallate papillae.
  Yamada Y, Takai S, Watanabe Y, Osaki A, Kawabata Y, Oike A, Hirayama A, Iwata S, Sanematsu K, Tabata S, Shigemura N.
  Biochem Biophys Res Commun. 2021 Apr 16;557:206-212. 

Effects of insulin signaling on mouse taste cell proliferation.
  Takai S, Watanabe Y, Sanematsu K, Yoshida R, Margolskee RF, Jiang P, Atsuta I, Koyano K, Ninomiya Y, Shigemura N.
  PLoS One. 2019 Nov 12;14(11):e0225190. 

N-acetyl cysteine induces quiescent-like pancreatic stellate cells from an active state and attenuates cancer-stroma interactions.
  Feng H, Moriyama T, Ohuchida K, Sheng N, Iwamoto C, Shindo K, Shirahane K, Ikenaga N, Nagai S, Nakata K, Mizumoto K, Nakamura M.
  J Exp Clin Cancer Res. 2021 Apr 15;40(1):133. 

Accumulation of Astrocytic Aquaporin 4 and Aquaporin 1 in Prion Protein Plaques.
  Sadashima S, Honda H, Suzuki SO, Shijo M, Aishima S, Kai K, Kira J, Iwaki T.
  J Neuropathol Exp Neurol. 2020 Apr 1;79(4):419-429. 

Ddhd1 knockout mouse as a model of locomotive and physiological abnormality in familial spastic paraplegia.
  Morikawa T, Ohishi H, Kosaka K, Shimojo T, Nagano A, Taniguchi I, Fujioka R, Moriyama K, Unoki M, Takahashi M, Nakao M, Izumi Y, Bamba T, Sasaki H, Miura S, Shibata H.
  Biosci Rep. 2021 Feb 26;41(2):BSR20204171.

Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss.
  Nakao Y, Fukuda T, Zhang Q, Sanui T, Shinjo T, Kou X, Chen C, Liu D, Watanabe Y, Hayashi C, Yamato H, Yotsumoto K, Tanaka U, Taketomi T, Uchiumi T, Le AD, Shi S, Nishimura F.
  Acta Biomater. 2021 Mar 1;122:306-324.

Combined application of geranylgeranylacetone and amelogenin promotes angiogenesis and wound healing in human periodontal ligament cells.
  Yamato H, Sanui T, Yotsumoto K, Nakao Y, Watanabe Y, Hayashi C, Aihara R, Iwashita M, Tanaka U, Taketomi T, Fukuda T, Nishimura F.
  J Cell Biochem. 2021 Feb 2. 

Detection of cutaneous prion protein deposits could help diagnose GPI-anchorless prion disease with neuropathy.
  Honda H, Matsuzono K, Satoh K, Fujisawa M, Suzuki SO, Furuyama C, Kitamoto T, Fujimoto S, Abe K, Iwaki T.
  Eur J Neurol. 2021 Jan 8.

PCBP2 Is Downregulated in Degenerating Neurons and Rarely Observed in TDP-43-Positive Inclusions in Sporadic Amyotrophic Lateral Sclerosis.
  Yoshimura M, Honda H, Sasagasako N, Mori S, Hamasaki H, Suzuki SO, Ishii T, Ninomiya T, Kira JI, Iwaki T.
  J Neuropathol Exp Neurol. 2020 Dec 14:nlaa148. 

Reconstitution of the oocyte transcriptional network with transcription factors.
  Hamazaki N, Kyogoku H, Araki H, Miura F, Horikawa C, Hamada N, Shimamoto S, Hikabe O, Nakashima K, Kitajima TS, Ito T, Leitch HG, Hayashi K.
  Nature. 2021 Jan;589(7841):264-269.

PD‑L1 and IDO‑1 expression in undifferentiated pleomorphic sarcoma: The associations with tumor infiltrating lymphocytes, dMMR and HLA class I.
  Ishihara S, Yamada Y, Iwasaki T, Yoshimoto M, Toda Y, Kohashi K, Yamamoto H, Matsumoto Y, Nakashima Y, Oda Y.
  Oncol Rep. 2021 Jan;45(1):379-389.

SLX4-XPF mediates DNA damage responses to replication stress induced by DNA-protein interactions.
  Ishimoto R, Tsuzuki Y, Matsumura T, Kurashige S, Enokitani K, Narimatsu K, Higa M, Sugimoto N, Yoshida K, Fujita M.
  J Cell Biol. 2021 Jan 4;220(1)

Sex Differences in Dendritic Spine Formation in the Hippocampus and Animal Behaviors in a Mouse Model of Hyperthyroidism.
  Niiyama T, Kuroiwa M, Yoshioka Y, Kitahara Y, Shuto T, Kakuma T, Ohta K, Nakamura KI, Nishi A, Noda M.
  Front Cell Neurosci. 2020 Sep 16;14:268. 

Glioendocrine System: Effects of Thyroid Hormones in Glia and their Functions in the Central Nervous System
  Noda M.
  Medical University | Volume 3: Issue 1

YAP signaling induces PIEZO1 to promote oral squamous cell carcinoma cell proliferation.
  Hasegawa K, Fujii S, Matsumoto S, Tajiri Y, Kikuchi A, Kiyoshima T.
  J Pathol. 2021 Jan;253(1):80-93.

Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity.
  Tadokoro T, Ikeda M, Ide T, Deguchi H, Ikeda S, Okabe K, Ishikita A, Matsushima S, Koumura T, Yamada KI, Imai H, Tsutsui H.
  JCI Insight. 2020 May 7;5(9)

Aberrant activation of bone marrow Ly6C high monocytes in diabetic mice contributes to impaired glucose tolerance.
  Ikeda Y, Sonoda N, Bachuluun B, Kimura S, Ogawa Y, Inoguchi T.
  PLoS One. 2020 Feb 25;15(2)

RagA, an mTORC1 activator, interacts with a hedgehog signaling protein, WDR35/IFT121.
  Sekiguchi T, Furuno N, Ishii T, Hirose E, Sekiguchi F, Wang Y, Kobayashi H.
  Genes Cells. 2019 Feb;24(2):151-161.

Src Mediates Epigallocatechin-3-O-Gallate-Elicited Acid Sphingomyelinase Activation.
  Kumazoe M, Kadomatsu M, Bae J, Otsuka Y, Fujimura Y, Tachibana H.
  Molecules. 2020 Nov 23;25(22):5481. 

Reduced Post-ischemic Brain Injury in Transient Receptor Potential Vanilloid 4 Knockout Mice.
  Tanaka K, Matsumoto S, Yamada T, Yamasaki R, Suzuki M, Kido MA, Kira JI.
  Front Neurosci. 2020 May 12;14:453.

SPOCK1 is a novel inducer of epithelial to mesenchymal transition in drug-induced gingival overgrowth.
  Alshargabi R, Sano T, Yamashita A, Takano A, Sanada T, Iwashita M, Shinjo T, Fukuda T, Sanui T, Kishida S, Nishimura F.
  Sci Rep. 2020 Jun 17;10(1):9785.

GRK5 Inhibition Attenuates Cartilage Degradation via Decreased NF-κB Signaling.
  Sueishi T, Akasaki Y, Goto N, Kurakazu I, Toya M, Kuwahara M, Uchida T, Hayashida M, Tsushima H, Bekki H, Lotz MK, Nakashima Y.
  Arthritis Rheumatol. 2020 Apr;72(4):620-631.

Fluorescence detection of metabolic activity of the fatty acid beta oxidation pathway in living cells.
  Uchinomiya S, Matsunaga N, Kamoda K, Kawagoe R, Tsuruta A, Ohdo S, Ojida A.
  Chem Commun (Camb). 2020 Mar 10;56(20):3023-3026.

The balance of forces generated by kinesins controls spindle polarity and chromosomal heterogeneity in tetraploid cells.
  Shu S, Iimori M, Wakasa T, Ando K, Saeki H, Oda Y, Oki E, Maehara Y.
  J Cell Sci. 2019 Dec 13;132(24):jcs231530.

Cytotoxicity of trifluridine correlates with the thymidine kinase 1 expression level.
  Kataoka Y, Iimori M, Niimi S, Tsukihara H, Wakasa T, Saeki H, Oki E, Maehara Y, Kitao H.
  Sci Rep. 2019 May 28;9(1):7964.

Intramolecular Interaction in LGN, an Adaptor Protein That Regulates Mitotic Spindle Orientation
  Hiroki Takayanagi  1 , Junya Hayase  1 , Sachiko Kamakura  1 , Kei Miyano  1 , Kanako Chishiki  1 , Satoru Yuzawa  1 , Hideki Sumimoto  2
  Front Immunol. 2020 Mar 11;11:432.

Inhibition of PI3Kδ Enhances Poly I:C-Induced Antiviral Responses and Inhibits Replication of Human Metapneumovirus in Murine Lungs and Human Bronchial Epithelial Cells.
  Fujita A, Kan-O K, Tonai K, Yamamoto N, Ogawa T, Fukuyama S, Nakanishi Y, Matsumoto K.
  J Biol Chem. 2019 Dec 20;294(51):19655-19666.

The TRPV4-AKT axis promotes oral squamous cell carcinoma cell proliferation via CaMKII activation.
  Fujita A, Kan-O K, Tonai K, Yamamoto N, Ogawa T, Fukuyama S, Nakanishi Y, Matsumoto K.
  Lab Invest. 2020 Feb;100(2):311-323.

Insulin deficiency promotes formation of toxic amyloid-β42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model.
  Imamura T, Yanagihara YT, Ohyagi Y, Nakamura N, Iinuma KM, Yamasaki R, Asai H, Maeda M, Murakami K, Irie K, Kira JI.
  Neurobiol Dis. 2020 Apr;137:104739.

GRWD1 directly interacts with p53 and negatively regulates p53 transcriptional activity.
  Fujiyama H, Tsuji T, Hironaka K, Yoshida K, Sugimoto N, Fujita M.
  J Biochem. 2020 Jan 1;167(1):15-24.

Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10.
  Yokoyama T, Yukuhiro M, Iwasaki Y, Tanaka C, Sankoda K, Fujiwara R, Shibuta A, Higashi T, Motoyama K, Arima H, Yoshida K, Sugimoto N, Morimoto H, Kosako H, Ohshima T, Fujita M.
  Sci Rep. 2019 Nov 14;9(1):16825.

UDP-Glucuronosyltransferase (UGT)-mediated attenuations of cytochrome P450 3A4 activity: UGT isoform-dependent mechanism of suppression.
  Miyauchi Y, Tanaka Y, Nagata K, Yamazoe Y, Mackenzie PI, Yamada H, Ishii Y.
  Br J Pharmacol. 2020 Mar;177(5):1077-1089.

Advantage of a Co-expression System for Estimating Physiological Effects of Functional Interaction Between Cytochrome P450 3A4 and Uridine ... al interaction of CYP3A4 and UGT2B7 by simply mixing the microsomes.
  Miyauchi Y, Yamada H, Ishii Y.
  BPB Reports 2, 61-66 (2019)

Investigation of the Endoplasmic Reticulum Localization of UDP-Glucuronosyltransferase 2B7 with Systematic Deletion Mutants.
  Miyauchi Y, Kimura S, Kimura A, Kurohara K, Hirota Y, Fujimoto K, Mackenzie PI, Tanaka Y, Ishii Y.
  Mol Pharmacol. 2019 May;95(5):551-562.

Cancer cell selective probe by mimicking EGCG.
  Kumazoe M, Hiroi S, Tanimoto Y, Miyakawa J, Yamanouchi M, Suemasu Y, Yoshitomi R, Murata M, Fujimura Y, Takahashi T, Tanaka H, Tachibana H.
  Biochem Biophys Res Commun. 2020 Mar 12. pii: S0006-291X(20)30496-4.

Identification of ZBTB24 protein domains and motifs for heterochromatin localization and transcriptional activation.
  Aktar S, Sasaki H, Unoki M.
  Genes Cells. 2019 Nov;24(11):746-755.

Effects of cigarette smoke on barrier function and tight junction proteins in the bronchial epithelium: protective role of cathelicidin LL-37.
  Tatsuta M, Kan-O K, Ishii Y, Yamamoto N, Ogawa T, Fukuyama S, Ogawa A, Fujita A, Nakanishi Y, Matsumoto K.
  Respir Res. 2019 Nov 9;20(1):251.

Enhanced junctional epithelial permeability in TRPV4-deficient mice.
  Kitsuki T, Yoshimoto RU, Aijima R, Hatakeyama J, Cao AL, Zhang JQ, Ohsaki Y, Mori Y, Kido MA.
  J Periodontal Res. 2019 Jul 25.

Expanded polyglutamine impairs normal nuclear distribution of fused in sarcoma and poly (rC)-binding protein 1 in Huntington's disease.
  Mori S, Honda H, Ishii T, Yoshimura M, Sasagasako N, Suzuki SO, Taniwaki T, Iwaki T.
  Neuropathology. 2019 Oct;39(5):358-367.

Dynactin is involved in Lewy body pathology.
  Shen C, Honda H, Suzuki SO, Maeda N, Shijo M, Hamasaki H, Sasagasako N, Fujii N, Iwaki T.
  Neuropathology. 2018 Dec;38(6):583-590.

Mitochondrial dysfunction and altered ribostasis in hippocampal neurons with cytoplasmic inclusions of multiple system atrophy.
  Maeda N, Honda H, Suzuki SO, Fujii N, Kira JI, Iwaki T.
  Neuropathology. 2018 Jul 1.

Hypoxia induces the dormant state in oocytes through expression of Foxo3.
  Shimamoto S, Nishimura Y, Nagamatsu G, Hamada N, Kita H, Hikabe O, Hamazaki N, Hayashi K.
  Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12321-12326.

Impaired Junctions and Invaded Macrophages in Oral Epithelia With Oral Pain.
  Yoshimoto RU, Aijima R, Ohyama Y, Yoshizumi J, Kitsuki T, Ohsaki Y, Cao AL, Danjo A, Yamashita Y, Kiyoshima T, Kido MA.
  J Histochem Cytochem. 2019 Apr;67(4):245-256.

Depolysulfidation of Drp1 induced by low-dose methylmercury exposure increases cardiac vulnerability to hemodynamic overload.
  Nishimura A, Shimoda K, Tanaka T, Toyama T, Nishiyama K, Shinkai Y, Numaga-Tomita T, Yamazaki D, Kanda Y, Akaike T, Kumagai Y, Nishida M.
  Sci Signal. 2019 Jun 25;12(587). pii: eaaw1920.

Ibudilast attenuates doxorubicin-induced cytotoxicity by suppressing formation of TRPC3 channel and NADPH oxidase 2 protein complexes.
  Nishiyama K, Numaga-Tomita T, Fujimoto Y, Tanaka T, Toyama C, Nishimura A, Yamashita T, Matsunaga N, Koyanagi S, Azuma YT, Ibuki Y, Uchida K, Ohdo S, Nishida M.
  Br J Pharmacol. 2019 Sep;176(18):3723-3738.

Mechanical stress accompanied with nuclear rotation is involved in the dormant state of mouse oocytes.
  Nagamatsu G, Shimamoto S, Hamazaki N, Nishimura Y, Hayashi K.
  Sci Adv. 2019 Jun 26;5(6):eaav9960.

The expression of keratan sulfate reveals a unique subset of microglia in the mouse hippocampus after pilocarpine-induced status epileptics.
  Ohgomori T, Jinno S.
  J Comp Neurol. 2019 Jun 25.

Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis.
  Harada Y, Zhang J, Imari K, Yamasaki R, Ni J, Wu Z, Yamamoto K, Kira JI, Nakanishi H, Hayashi Y.
  Pain. 2019 Apr 30.

Stromal Interaction Molecule Deficiency in T Cells Promotes Spontaneous Follicular Helper T Cell Development and Causes Type 2 Immune Disorders.
  Oh-Hora M, Lu X, Shiokawa M, Takayanagi H, Yamasaki S.
  J Immunol. 2019 May 1;202(9):2616-2627.

Wnt/β-catenin signaling, which is activated in odontomas, reduces Sema3A expression to regulate odontogenic epithelial cell proliferation and tooth germ development.
  Fujii S, Nagata K, Matsumoto S, Kohashi KI, Kikuchi A, Oda Y, Kiyoshima T, Wada N.
  Sci Rep. 2019 Mar 12;9(1):4257.

Inhibiting the MCM8-9 complex selectively sensitizes cancer cells to cisplatin and olaparib.
  Morii I, Iwabuchi Y, Mori S, Suekuni M, Natsume T, Yoshida K, Sugimoto N, Kanemaki MT, Fujita M.
  Cancer Sci. 2019 Mar;110(3):1044-1053.

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.
  Watanabe S, Fujiyama H, Takafuji T, Kayama K, Matsumoto M, Nakayama KI, Yoshida K, Sugimoto N, Fujita M.
  J Cell Sci. 2018 Aug 3;131(15).

Association of Missense Polymorphism in HSD3B1 With Outcomes Among Men With Prostate Cancer Treated With Androgen-Deprivation Therapy or Abiraterone.
  Shiota M, Narita S, Akamatsu S, Fujimoto N, Sumiyoshi T, Fujiwara M, Uchiumi T, Habuchi T, Ogawa O, Eto M.
  JAMA Netw Open. 2019 Feb 1;2(2):e190115.

The transcription factor NKX2-3 mediates p21 expression and ectodysplasin-A signaling in the enamel knot for cusp formation in tooth development.
  Han X, Yoshizaki K, Miyazaki K, Arai C, Funada K, Yuta T, Tian T, Chiba Y, Saito K, Iwamoto T, Yamada A, Takahashi I, Fukumoto S.
  J Biol Chem. 2018 Sep 21;293(38):14572-14584.

Establishment of a rapid and simple assay for measuring serum trehalase activity.
  Terada S, Sakemoto M, Kawanobe Y, Kawano M, Tateishi T, Hotta T, Kang D, Kayamori Y and Hokazono E.
  Int J Anal Bio-Sci, 6, 2, 19-24, Vol. 6, No2 (2018), 2018.06

Folic acid-mediated mitochondrial activation for protection against oxidative stress in human dental pulp stem cells derived from deciduous teeth.
  Zhang Y, Kato H, Sato H, Yamaza H, Hirofuji Y, Han X, Masuda K, Nonaka K.
  Biochem Biophys Res Commun. 2019 Jan 15;508(3):850-856.

Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion.
  Matsuda T, Irie T, Katsurabayashi S, Hayashi Y, Nagai T, Hamazaki N, Adefuin AMD, Miura F, Ito T, Kimura H, Shirahige K, Takeda T, Iwasaki K, Imamura T, Nakashima K.
  Neuron. 2018 Dec 28.

Osteoblastic differentiation improved by bezafibrate-induced mitochondrial biogenesis in deciduous tooth-derived pulp stem cells from a child with Leigh syndrome.
  Han X, Nonaka K, Kato H, Yamaza H, Sato H, Kifune T, Hirofuji Y, Masuda K.
  Biochem Biophys Rep. 2018 Nov 28;17:32-37.

Effects of Derinat on ischemia-reperfusion-induced pressure ulcer mouse model.
  Liu J, Rybakina EG, Korneva EA, Noda M.
  J Pharmacol Sci. 2018 Oct;138(2):123-130.

Neuropathic pain inhibitor, RAP-103, is a potent inhibitor of microglial CCL1/CCR8.
  Noda M, Tomonaga D, Kitazono K, Yoshioka Y, Liu J, Rousseau JP, Kinkead R, Ruff MR, Pert CB.
  Neurochem Int. 2018 Oct;119:184-189.

Altered development of dopaminergic neurons differentiated from stem cells from human exfoliated deciduous teeth of a patient with Down syndrome.
  Pham TTM, Kato H, Yamaza H, Masuda K, Hirofuji Y, Sato H, Nguyen HTN, Han X, Zhang Y, Taguchi T, Nonaka K.
  BMC Neurol. 2018 Aug 31;18(1):132.

The DnaA AAA+ Domain His136 Residue Directs DnaB Replicative Helicase to the Unwound Region of the Replication Origin, oriC.
  Sakiyama Y, Nishimura M, Hayashi C, Akama Y, Ozaki S, Katayama T.
  Front Microbiol. 2018 Aug 31;9:2017.

Np95/Uhrf1 regulates tumor suppressor gene expression of neural stem/precursor cells, contributing to neurogenesis in the adult mouse brain.
  Murao N, Matsubara S, Matsuda T, Noguchi H, Mutoh T, Mutoh M, Koseki H, Namihira M, Nakashima K.
  Neurosci Res. 2018 May 31.

HMGB2 expression is associated with transition from a quiescent to an activated state of adult neural stem cells.
  Kimura A, Matsuda T, Sakai A, Murao N, Nakashima K.
  Dev Dyn. 2018 Jan;247(1):229-238.

Regulatory dynamics in the ternary DnaA complex for initiation of chromosomal replication in Escherichia coli.
  Sakiyama Y, Kasho K, Noguchi Y, Kawakami H, Katayama T.
  Nucleic Acids Res. 2017 Dec 1;45(21):12354-12373.



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